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Sitamaquine (tosylate)
Products Details
Product Description
– Sitamaquine (WR 6026) tosylate, an orally active 8-aminoquinoline analog, is an antileishmanial agent. Sitamaquine is a lipophilic weak base that rapidly accumulates in acidic compartments of Leishmania spp., mainly in acidocalcisomes[1].
Web ID
– HY-19688B
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C28H41N3O4S
References
– [1]López-MartÃn C, et al. Sitamaquine sensitivity in Leishmania species is not mediated by drug accumulation in acidocalcisomes. Antimicrob Agents Chemother. 2008;52(11):4030-4036.
CAS Number
– 1019640-33-5
Molecular Weight
– 515.71
SMILES
– CC1=CC=NC2=C(NCCCCCCN(CC)CC)C=C(OC)C=C12.O=S(C3=CC=C(C)C=C3)(O)=O
Clinical Information
– Phase 2
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Parasite
Isoform
– Leishmania
Pathway
– Anti-infection
Product type
– Reference compound
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