Download Files:
Products Details
Product Description
– Sirtuin-1 inhibitor 1 (Compound 8) is an inhibitor of Sirtuin-1 that plays important roles in obesity-induced diabetes and aging-related diseases[1].
Web ID
– HY-156781
Shipping
– Room temperature
Molecular Formula
– C20H17N3O2
References
– [1]Anastasiia Gryniukova, et al. AI-Powered Virtual Screening of Large Compound Libraries Leads to the Discovery of Novel Inhibitors of Sirtuin-1. J Med Chem. 2023 Aug 10;66(15):10241-10251.
CAS Number
– 945114-10-3
Molecular Weight
– 331.37
SMILES
– O=C(NC1=CC=C(NC(C2=CC=CC=C2)=O)C=C1)NC3=CC=CC=C3
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Sirtuin
Isoform
– SIRT1
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
