Products Details

Product Description

– SIRT5 inhibitor 9 (compound 14) is a competitive inhibitor (IC50: 4.07 μM) of sirtuin SIRT5 with anticancer potential[1].

Web ID

– HY-149525

Shipping

– Room temperature

Molecular Formula

– C24H29ClN8O4S

References

– [1]Wang L, et al. Design, synthesis and biological evaluation of 2,4,6- trisubstituted triazine derivatives as new nonpeptide small-molecule SIRT5 inhibitors. Bioorg Med Chem. 2023 Oct 1;93:117455.. .

Molecular Weight

– 561.06

SMILES

– ClC(C=CC=C1)=C1NC2=NC(NC3=CC(OC)=CC(OC)=C3)=NC(NCCCNC(NCCC(O)=O)=S)=N2

Clinical Information

– No Development Reported

Research Area

– cancer

Solubility

– 10 mM in DMSO

Target

– Sirtuin

Pathway

– Cell Cycle/DNA Damage;Epigenetics

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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