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Products Details
Product Description
– SIRT5 inhibitor 8 (compound 10) is a competitive inhibitor (IC50: 5.38 μM) of sirtuin SIRT5 with anticancer potential[1].
Web ID
– HY-149524
Shipping
– Room temperature
Molecular Formula
– C22H25ClN8O2S
References
– [1]Wang L, et al. Design, synthesis and biological evaluation of 2,4,6- trisubstituted triazine derivatives as new nonpeptide small-molecule SIRT5 inhibitors. Bioorg Med Chem. 2023 Oct 1;93:117455.. .
Molecular Weight
– 501.00
SMILES
– ClC(C=CC=C1)=C1NC2=NC(NC3=CC=CC=C3)=NC(NCCCNC(NCCC(O)=O)=S)=N2
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– Sirtuin
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
