Sipatrigine

$260$286

Products Details

Product Description

– Sipatrigine (619C89), a neuroprotective agent, is a glutamate release inhibitor, voltage-dependent sodium channel and calcium channel inhibitor, penetrating the central nervous system. Has the potential in the study for focal cerebral ischemia and stroke[1][2].

Web ID

– HY-108335

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C15H16Cl3N5

References

– [1]Leach MJ, et al. BW619C89, a glutamate release inhibitor, protects against focal cerebral ischemic damage. Stroke. 1993 Jul;24(7):1063-7.|[2]Atticus H. Hainsworth, et al. Sipatrigine (BW 619C89) is a Neuroprotective Agent and a Sodium Channel and Calcium Channel Inhibitor. CNS Drug Reviews. Vol. 6, No. 2, pp. 111-134.

CAS Number

– 130800-90-7

Molecular Weight

– 372.68

Compound Purity

– 99.29

SMILES

– NC1=NC(N2CCN(C)CC2)=NC=C1C3=CC(Cl)=CC(Cl)=C3Cl

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– DMSO : 250 mg/mL (ultrasonic)

Target

– Calcium Channel;Sodium Channel

Pathway

– Membrane Transporter/Ion Channel;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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