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Sipatrigine
SKU
HY-108335-10mM/1mL
Category Reference compound
Tags Calcium Channel;Sodium Channel, Membrane Transporter/Ion Channel;Neuronal Signaling, Neurological Disease
$260 – $286
Products Details
Product Description
– Sipatrigine (619C89), a neuroprotective agent, is a glutamate release inhibitor, voltage-dependent sodium channel and calcium channel inhibitor, penetrating the central nervous system. Has the potential in the study for focal cerebral ischemia and stroke[1][2].
Web ID
– HY-108335
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C15H16Cl3N5
References
– [1]Leach MJ, et al. BW619C89, a glutamate release inhibitor, protects against focal cerebral ischemic damage. Stroke. 1993 Jul;24(7):1063-7.|[2]Atticus H. Hainsworth, et al. Sipatrigine (BW 619C89) is a Neuroprotective Agent and a Sodium Channel and Calcium Channel Inhibitor. CNS Drug Reviews. Vol. 6, No. 2, pp. 111-134.
CAS Number
– 130800-90-7
Molecular Weight
– 372.68
Compound Purity
– 99.29
SMILES
– NC1=NC(N2CCN(C)CC2)=NC=C1C3=CC(Cl)=CC(Cl)=C3Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– Calcium Channel;Sodium Channel
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.