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SIK2-IN-1
$625 – $1,000
Products Details
Product Description
– SIK2-IN-1 (compound 8g) is a potent SIK2 inhibitor over other AMPK kinases. SIK2-IN-1 exhibits favorable in vitro ADMET profiles and decent cellular activities[1].
Web ID
– HY-153975
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C25H28F3N7O2S
References
– [1]Zhu W, et al. Discovery of novel and selective SIK2 inhibitors by the application of AlphaFold structures and generative models. Bioorg Med Chem. 2023 Jul 13;91:117414.
Molecular Weight
– 547.60
Compound Purity
– 99.26
SMILES
– COC1=C2C(CCN(CC(F)(F)F)C2=O)=CC(C3=CN=C(NC4=CC(N5CCN(C)CC5)=NC(C)=N4)S3)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Salt-inducible Kinase (SIK)
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
