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Products Details
Product Description
– Sibenadet hydrochloride (AR-C68397AA) is a dual D2 dopamine receptor, beta2-adrenoceptor agonist with bronchodilator activity. Investigation in animal models of key chronic obstructive pulmonary disease (COPD) symptoms has demonstrated that Sibenadet hydrochloride effectively inhibits sensory nerve activity, thereby reducing reflex cough, mucus production and tachypnoea.
Web ID
– HY-124270
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C22H29ClN2O5S2
References
– [1]Ind PW, Laitinen L, Laursen L, et al. Early clinical investigation of Viozan (sibenadet HCl), a novel D2 dopamine receptor, beta2-adrenoceptor agonist for the treatment of chronic obstructive pulmonary disease symptoms. Respir Med. 2003;97 Suppl A:S9-S21.
CAS Number
– 154189-24-9
Molecular Weight
– 501.06
SMILES
– O=C1SC2=C(C=CC(O)=C2N1)CCNCCS(=O)(CCCOCCC3=CC=CC=C3)=O.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Adrenergic Receptor;Dopamine Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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