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Products Details
Product Description
– SHR168442 is a modulator of retinoid-related orphan receptor gamma (RORγ) with an IC50 value of 0.035 μM.
Web ID
– HY-115879
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C23H25Cl2F2N3O3S
References
– [1]Yan Y, et al. Benzimidazole derivatives as modulators of retinoid-related orphan receptor gamma (rorϒ) and pharmaceutical uses thereof. WO2019213470 A1.
CAS Number
– 2382961-86-4
Molecular Weight
– 532.43
SMILES
– OCC[C@H](C1=CC=C(C=C1)S(CC)(=O)=O)C2=NC3=CC(Cl)=C(N4CCC(F)(CC4)F)C(Cl)=C3N2
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– ROR
Isoform
– RORγ
Pathway
– Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
