Download Files:
SHP2-IN-18
Products Details
Product Description
– SHP2-IN-18 (compound 183) is a SHP2 inhibitor with an IC50 value of 3 nM. SHP2-IN-18 can be used for glioblastoma research[1].
Web ID
– HY-155274
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C26H27FN6
References
– [1]Sabnis RW. Novel Pyrazolopyrazine Compounds as SHP2 Inhibitors for Treating Glioblastoma. ACS Med Chem Lett. 2023 Sep 19;14(10):1336-1337.
CAS Number
– 2941498-87-7
Molecular Weight
– 442.53
SMILES
– FC1=CC(C)=CC=C1C2=C(C)N=C(N3CCC4(CC(N=CC=C5)=C5[C@H]4N)CC3)C6=CC=NN26
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– SHP2
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.