Products Details

Product Description

– SHP2-IN-16 (compound 222) is a SHP2 inhibitor with an IC50 value of 1 nM. SHP2-IN-16 can be used for glioblastoma research[1].

Web ID

– HY-155272

Shipping

– Room temperature

Molecular Formula

– C25H24F2N6O

References

– [1]Sabnis RW. Novel Pyrazolopyrazine Compounds as SHP2 Inhibitors for Treating Glioblastoma. ACS Med Chem Lett. 2023 Sep 19;14(10):1336-1337.

Molecular Weight

– 462.49

SMILES

– FC1=C(F)C=CC=C1C2=C(C)N=C(N3CCC4(CC(N=C(O)C=C5)=C5[C@H]4N)CC3)C6=CC=NN26

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– SHP2

Pathway

– Protein Tyrosine Kinase/RTK

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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