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Products Details
Product Description
– SGLT1/2-IN-2 demonstrates potent dual inhibitory activities (IC50 = 96 nM for SGLT1 and IC50 = 1.3 nM for SGLT2).
Web ID
– HY-145357
Shipping
– Room temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C23H26F2O7
References
– [1]Xu G, et al. 5,5-Difluoro- and 5-Fluoro-5-methyl-hexose-based C-Glucosides as potent and orally bioavailable SGLT1 and SGLT2 dual inhibitors. Bioorg Med Chem Lett. 2020 Sep 1;30(17):127387.
CAS Number
– 2387812-73-7
Molecular Weight
– 452.45
SMILES
– O[C@H]1[C@H](C2=CC(CC3=CC=C(OCCC4)C4=C3)=C(C=C2O)OC)O[C@@H](C(F)([C@@H]1O)F)CO
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– SGLT
Isoform
– SGLT1;SGLT2
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
