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SGK1-IN-4
$450 – $3,800
Products Details
Product Description
– SGK1-IN-4 (compound 17a) is a highly selective, orally active SGK1 inhibitor. SGK1-IN-4 can be used for osteoarthritis research[1].
Web ID
– HY-142687
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C23H21ClFN5O4S
References
– [1]Nis Halland, et al. Rational Design of Highly Potent, Selective, and Bioavailable SGK1 Protein Kinase Inhibitors for the Treatment of Osteoarthritis. J Med Chem. 2022 Jan 27;65(2):1567-1584.
CAS Number
– 1628048-93-0
Molecular Weight
– 517.96
Compound Purity
– 97.19
SMILES
– O=S(NC(C=C1)=CC=C1C2=NC(O[C@@H]3CC[C@H](CC3)O)=C4C(NN=C4)=N2)(C5=C(C=CC(Cl)=C5)F)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– SGK
Isoform
– SGK1
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
