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Sevelamer (hydrochloride)
$90 – $324
Products Details
Product Description
– Sevelamer hydrochloride is an orally active and phosphate binding agent used for research of hyperphosphatemia with chronic kidney disease. Sevelamer hydrochloride consists of polyallylamine that is crosslinked with epichlorohydrin[1][2][3].
Web ID
– HY-13995A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Molecular Formula
– (C3H7N.C3H5ClO)x.xHCl
References
– [1]Sevelamer, From Wikipedia|[2]Bennis Y, et al. The Effect of Sevelamer on Serum Levels of Gut-Derived Uremic Toxins: Results from In Vitro Experiments and A Multicenter, Double-Blind, Placebo-Controlled, Randomized Clinical Trial. Toxins (Basel). 2019 May 17;11(5):279. |[3]Susan C Schiavi, et al. Npt2b deletion attenuates hyperphosphatemia associated with CKD. J Am Soc Nephrol. 2012 Oct;23(10):1691-700.
CAS Number
– 152751-57-0
Molecular Weight
– 186.08 (monomer)
Compound Purity
– 98.0
SMILES
– NCC(CC(CC)CNCC(O)CNCC(C)CC(CC)CN)CC.[m].Cl.[m].[c].[b].[a]
Clinical Information
– Launched
Research Area
– Others
Solubility
– DMSO : < 1 mg/mL|H2O : 1 mg/mL (ultrasonic)
Target
– Autophagy;FXR
Pathway
– Autophagy;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
