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Sevasemten
$130 – $1,200
Products Details
Product Description
– Sevasemten is an allosteric inhibitor of skeletal muscle myosin. Sevasemten exhibits selectively myosin inhibition with IC50s of ≤10 μM (skeletal), >100 μM (cardiac), respectively[1][2].
Web ID
– HY-148799
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Molecular Formula
– C16H11F4N5O2
References
– [1]WHO Drug Information-World Health Organization (WHO).|[2]Russell Alan, et al. Preparation of substituted pyridazinones for use in the treatment of neuromuscular diseases: World Intellectual Property Organization, WO2021231615. 2021-11-18.
CAS Number
– 2417395-15-2
Molecular Weight
– 381.28
Compound Purity
– 99.46
SMILES
– O=C1C=CC(C2=CN=C(OCC(F)(F)F)N=C2)=NN1CC3=CC(F)=CN=C3
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– Myosin
Pathway
– Cytoskeleton
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
