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Products Details
Product Description
– SETD7-IN-1 (compound 7) is a PFI-2 (HY-18627) analogue. SETD7-IN-1 is a substrate and inhibitor of histone lysine methyltransferase SETD7, with an IC50 of 0.96 ± 0.10 µM[1].
Web ID
– HY-156455
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H24FN3O4S
References
– [1]Porzberg M, et al. (R)-PFI-2 Analogues as Substrates and Inhibitors of Histone Lysine Methyltransferase SETD7. ChemMedChem. 2023 Oct 23:e202300457.
Molecular Weight
– 421.49
SMILES
– FC1=CC(S(=O)(N[C@H](CC2=CC=CC=C2)C(NCCO)=O)=O)=CC3=C1CNCC3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Histone Methyltransferase
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
