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SEQ-9
Products Details
Product Description
– SEQ-9 is an orally active Mycobacterium tuberculosis (Mtb) 23S bacterial ribosome inhibitor with an IC50 of approximately 170 nM for unmethylated Mtb ribosomes. SEQ-9 also potently inhibits A2296 methylated ribosomes. SEQ-9 can be used to study bacterial infection and drug resistance[1].
Web ID
– HY-153222
Shipping
– Room temperature
Molecular Formula
– C60H100N4O20S
References
– [1]ZHICHENG CUI. Structural Studies of Mycobacterium Tuberculosis Ribosome: From Translational Regulation to Drug Resistance. Texas A&M University. 2021 Apr 12.
Molecular Weight
– 1229.52
SMILES
– C[C@H]([C@@]([C@@H]1C)([H])OC([C@H](C)[C@H]([C@@H]([C@H]([C@@H](C)C[C@@](OC(NC(C)(C)CNS(C2=CC=CC=C2)(=O)=O)=O)(C)C([C@@H]([C@@H]1OC(CC(C)C)=O)C)=O)O[C@]3([H])O[C@]([H])(C)C/C([C@H]3O)=N/OC)C)O[C@]4([H])O[C@@H](C)CN(C)[C@H](C)C4)=O)O[C@@]5([H])[C@H](OC)[C@H](OC)[C@H](O)[C@](C)([H])O5
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
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