Products Details

Product Description

– SEQ-9 is an orally active Mycobacterium tuberculosis (Mtb) 23S bacterial ribosome inhibitor with an IC50 of approximately 170 nM for unmethylated Mtb ribosomes. SEQ-9 also potently inhibits A2296 methylated ribosomes. SEQ-9 can be used to study bacterial infection and drug resistance[1].

Web ID

– HY-153222

Shipping

– Room temperature

Molecular Formula

– C60H100N4O20S

References

– [1]ZHICHENG CUI. Structural Studies of Mycobacterium Tuberculosis Ribosome: From Translational Regulation to Drug Resistance. Texas A&M University. 2021 Apr 12.

Molecular Weight

– 1229.52

SMILES

– C[C@H]([C@@]([C@@H]1C)([H])OC([C@H](C)[C@H]([C@@H]([C@H]([C@@H](C)C[C@@](OC(NC(C)(C)CNS(C2=CC=CC=C2)(=O)=O)=O)(C)C([C@@H]([C@@H]1OC(CC(C)C)=O)C)=O)O[C@]3([H])O[C@]([H])(C)C/C([C@H]3O)=N/OC)C)O[C@]4([H])O[C@@H](C)CN(C)[C@H](C)C4)=O)O[C@@]5([H])[C@H](OC)[C@H](OC)[C@H](O)[C@](C)([H])O5

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– Bacterial

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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