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Sepimostat
$300 – $2,350
Products Details
Product Description
– Sepimostat (FUT-187 free base) exhibits neuroprotective activity via NR2B N-methyl-D-aspartate receptor antagonism at the Ifenprodil-binding site of the NR2B subunit. Sepimostat inhibits the Ifenprodil binding with a Ki value of 27.7 µM[1].
Web ID
– HY-136299
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C21H19N5O2
References
– [1]Masahiro Fuwa, et al. Nafamostat and Sepimostat Identified as Novel Neuroprotective Agents via NR2B N-methyl-D-aspartate Receptor Antagonism Using a Rat Retinal Excitotoxicity Model. Sci Rep. 2019 Dec 31;9(1):20409.
CAS Number
– 103926-64-3
Molecular Weight
– 373.41
Compound Purity
– 99.79
SMILES
– O=C(OC1=CC=C2C=C(C(N)=N)C=CC2=C1)C3=CC=C(NC4=NCCN4)C=C3
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 6.25 mg/mL (ultrasonic)
Target
– iGluR
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
