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Senexin A
$100 – $1,152
Products Details
Product Description
– Senexin A is a CDK8 inhibitor with an IC50 of 280 nM.
Web ID
– HY-15681
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C17H14N4
References
– [1]Porter DC, et al. Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13799-804.
CAS Number
– 1366002-50-7
Molecular Weight
– 274.32
Compound Purity
– 99.85
SMILES
– N#CC1=CC=C2C(C(NCCC3=CC=CC=C3)=NC=N2)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 100 mg/mL
Target
– CDK
Isoform
– CDK19;CDK8
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
