Products Details

Product Description

– SEN461 is a potent and orally active Wnt pathway inhibitor. SEN461 shows effective anti-tumor activity and can be used for GBM research[1].

Web ID

– HY-120864

Shipping

– Room temperature

Molecular Formula

– C25H34N4O6

References

– [1]Nencini, A, et al. Structure–activity relationship and properties optimization of a series of Quinazoline-2,4-diones as inhibitors of the canonical Wnt pathway. European Journal of Medicinal Chemistry, 95, 526–545.

CAS Number

– 1287727-28-9

Molecular Weight

– 486.56

SMILES

– O=C(N(C1=C(C2=O)C=C(C=C1)OC)C)N2C[C@H]3CC[C@@H](CC3)C(N4CCN(CC4)C(COC)=O)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Wnt

Pathway

– Stem Cell/Wnt

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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