Download Files:
SEMBL
SKU
HY-124651-10 mg
Category Reference compound
Tags Cancer; Inflammation/Immunology, Metabolic Enzyme/Protease;NF-κB, MMP;NF-κB
$90 – $280
Products Details
Product Description
– SEMBL is a potent NF-κB inhibitor. SEMBL can inhibit NF-κB-DNA binding, and also inhibits NF-κB-dependent inflammatory cytokine secretions. SEMBL inhibits cancer cell migration and invasion via decreasing MMP expression. SEMBL can be used for researching anticancer[1].
Web ID
– HY-124651
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C12H11NO4
References
– [1]Umezawa K, et al. Inhibition of matrix metalloproteinase expression and cellular invasion by NF-κB inhibitors of microbial origin. Biochim Biophys Acta Proteins Proteom. 2020;1868(6):140412.
CAS Number
– 1443448-82-5
Molecular Weight
– 233.22
Compound Purity
– 99.40
SMILES
– O=C(N[C@@H](C1=C)COC1=O)C2=CC=CC=C2O
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– MMP;NF-κB
Pathway
– Metabolic Enzyme/Protease;NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.