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sEH inhibitor-16

Products Details

Product Description

– sEH inhibitor-16 is a soluble epoxide hydrolase (sEH) inhibitors with an IC50 of 2 nM. sEH inhibitor-16 reduces the inflammatory damage in Cerulein (HY-A0190)-induced acute pancreatitis (AP) in mice and can be used for inflammation/immunology research[1].

Web ID

– HY-155029

Shipping

– Room temperature

Molecular Formula

– C30H37N3O

References

– [1]Musella S, et.al. Design, Synthesis, and Pharmacological Characterization of a Potent Soluble Epoxide Hydrolase Inhibitor for the Treatment of Acute Pancreatitis. J Med Chem. 2023 Jul 13;66(13):9201-9222.

Molecular Weight

– 455.63

SMILES

– O=C(NC1=CC2=C(N(CC3=CC=C(C(C)C)C=C3)C=C2)C=C1)NCC4(C5)C[C@H](C[C@H]5C6)C[C@H]6C4

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– Epoxide Hydrolase

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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