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sEH inhibitor-14

Products Details

Product Description

– sEH inhibitor-14 (compound 33) is a benzoxazolone-5-urea analogue. In addition, sEH inhibitor-14 is a soluble Epoxide Hydrolase (sEH) inhibitor (IC50=0.39 nM)[1].

Web ID

– HY-148573

Shipping

– Room temperature

Applications

– Metabolism-sugar/lipid metabolism

Molecular Formula

– C16H12F3N3O4

References

– [1]Gur Maz T, et al. Benzoxazolone-5-Urea Derivatives as Human Soluble Epoxide Hydrolase (sEH) Inhibitors. ACS Omega, 2023.

CAS Number

– 2890221-26-6

Molecular Weight

– 367.28

SMILES

– O=C(NC1=CC2=C(OC(N2)=O)C=C1)NCC3=C(C=CC=C3)OC(F)(F)F

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease; Inflammation/Immunology; Cardiovascular Disease

Solubility

– 10 mM in DMSO

Target

– Epoxide Hydrolase

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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