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Seconeolitsine
SKU
HY-N10495-1 mg
Category Natural Products
Tags Anti-infection;Cell Cycle/DNA Damage, Antibiotic;Bacterial;Topoisomerase, Infection
$250 – $5,050
Products Details
Product Description
– Seconeolitsine, an antibiotic, and is an inhibitor of targeting topoisomerase I (TopA). Seconeolitsine also is a new antimicrobial agent that can inhibit S. pneumoniae growth. Seconeolitsine can inhibit TopA relaxation activity with an IC50 value of 17 μM. Seconeolitsine can be used for the research of S. pneumoniae infections resistant to other antibiotics[1].
Web ID
– HY-N10495
Storage Temperature
– 4°C (Powder, stored under nitrogen)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C19H17NO4
References
– [1]MarÃa Teresa GarcÃa, et al. New alkaloid antibiotics that target the DNA topoisomerase I of Streptococcus pneumonia. J Biol Chem. 2011 Feb 25;286(8):6402-13.
CAS Number
– 2650074-56-7
Molecular Weight
– 323.34
Compound Purity
– 95.0
SMILES
– CNCCC1=C2C=CC3=CC(OCO4)=C4C=C3C2=C5OCOC5=C1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Bacterial;Topoisomerase
Isoform
– Topo I
Pathway
– Anti-infection;Cell Cycle/DNA Damage
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.