Products Details

Product Description

– Seco-DUBA hydrochloride is a toxin for ADC drug SYD985[1].

Web ID

– HY-132180

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C29H23ClN4O4.xHCl

References

– [1]Ronald C Elgersma, et al. Design, Synthesis, and Evaluation of Linker-Duocarmycin Payloads: Toward Selection of HER2-Targeting Antibody-Drug Conjugate SYD985. Mol Pharm. 2015 Jun 1;12(6):1813-35.

CAS Number

– 1795733-93-5

Molecular Weight

– N/A

SMILES

– ClC[C@H]1C2=C(C=C(C3=CC=CC(C)=C32)O)N(C1)C(C4=CN(C=C(C=C5)NC(C6=CC=C(C=C6)O)=O)C5=N4)=O.Cl[H].[x]

Clinical Information

– No Development Reported

Research Area

– Cancer; Inflammation/Immunology

Solubility

– DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)

Target

– ADC Cytotoxin

Pathway

– Antibody-drug Conjugate/ADC Related

Product type

– ADC Related

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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