Download Files:
Products Details
Product Description
– Seco-DUBA hydrochloride is a toxin for ADC drug SYD985[1].
Web ID
– HY-132180
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C29H23ClN4O4.xHCl
References
– [1]Ronald C Elgersma, et al. Design, Synthesis, and Evaluation of Linker-Duocarmycin Payloads: Toward Selection of HER2-Targeting Antibody-Drug Conjugate SYD985. Mol Pharm. 2015 Jun 1;12(6):1813-35.
CAS Number
– 1795733-93-5
Molecular Weight
– N/A
SMILES
– ClC[C@H]1C2=C(C=C(C3=CC=CC(C)=C32)O)N(C1)C(C4=CN(C=C(C=C5)NC(C6=CC=C(C=C6)O)=O)C5=N4)=O.Cl[H].[x]
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– ADC Cytotoxin
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
