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(S,E)-TCO2-PEG8-acid
Products Details
Product Description
– (S)-TCO-PEG8-acid is a click chemistry PEG linker with a terminal carboxylic acid(COOH) group. The terminal carboxylic acid is reactive with primary amine groups to form a stable amide bond. (S)-TCO-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. (S)-TCO-PEG8-acid is longer than (S)-TCO-PEG3-acid[1].
Web ID
– HY-141161A
Shipping
– Room temperature
Molecular Formula
– C28H51NO12
References
– [1]Dion Voerman, et al. Synthetic Semiflexible and Bioactive Brushes. Biomacromolecules. 2019 Jul 8;20(7):2587-2597.
Molecular Weight
– 593.70
SMILES
– O=C(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)O[C@@H]1/C=C/CCCCC1
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– PROTAC Linkers
Pathway
– PROTAC
Product type
– Reference compound
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