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SDMA-d6
$250 – $2,850
Products Details
Product Description
– SDMA-d6 is the deuterium labeled SDMA. SDMA (Symmetric dimethylarginine) is an endogenous inhibitor of nitric oxide (NO) synthase activity[1][2].
Web ID
– HY-101410S
Storage Temperature
– -20°C (Powder, stored under nitrogen)
Shipping
– Blue Ice
Molecular Formula
– C8H12D6N4O2
References
– [1]Veldink H, et al. Effects of chronic SDMA infusion on glomerular filtration rate, blood pressure, myocardial function and renal histology in C57BL6/J mice. Nephrol Dial Transplant. 2013 Jun;28(6):1434-9.|[2]Bode-Böger SM,et al. Symmetrical dimethylarginine: a new combined parameter for renal function and extent ofcoronary artery disease.|[3]Schepers E, et al. Symmetric dimethylarginine as a proinflammatory agent in chronic kidney disease.Clin J Am Soc Nephrol. 2011 Oct;6(10):2374-83.|[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[5]Nabity MB, et al. Symmetric Dimethylarginine Assay Validation, Stability, and Evaluation as a Marker for the EarlyDetection of Chronic Kidney Disease in Dogs. J Vet Intern Med. 2015 Jul-Aug;29(4):1036-44.
CAS Number
– 1331888-08-4
Molecular Weight
– 208.29
Compound Purity
– 99.03
SMILES
– OC([C@@H](N)CCC/N=C(NC([2H])([2H])[2H])/NC([2H])([2H])[2H])=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– H2O : 125 mg/mL (ultrasonic)
Target
– Endogenous Metabolite
Pathway
– Metabolic Enzyme/Protease
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
