Download Files:
SCH-900271
SKU
HY-111143-Get quote
Category Reference compound
Tags Membrane Transporter/Ion Channel;Neuronal Signaling, Metabolic Disease, nAChR
Products Details
Product Description
– SCH-900271 is an orally active, potent nicotinic acid receptor (NAR) agonist with an EC50 of 2 nM in the hu-GPR109a assay. SCH-900271 exhibits dose-dependent inhibition of plasma free fatty acid (FFA). SCH-900271 has an improved therapeutic window to flushing[1].
Web ID
– HY-111143
Shipping
– Room temperature
Molecular Formula
– C14H16N2O4
References
– [1]Anandan Palani, et al. Discovery of SCH 900271, a Potent Nicotinic Acid Receptor Agonist for the Treatment of Dyslipidemia. ACS Med Chem Lett. 2011 Nov 24;3(1):63-8.
CAS Number
– 915210-50-3
Molecular Weight
– 276.29
SMILES
– O=C1NC2=C(C(CCCC3(C)CC3)=CC(O2)=O)C(N1)=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– nAChR
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.