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Scandenolide
SKU
HY-118019-Get quote
Category Reference compound
Tags Cardiovascular Disease, GPCR/G Protein, Platelet-activating Factor Receptor (PAFR)
Products Details
Product Description
– Scandenolide is a sesquiterpene lactone that can be found in Philippines medicinal plant Mikania cordata. Scandenolide inhibits leukotriene and platelet activating factor synthesis in leukocytes[1][2].
Web ID
– HY-118019
Shipping
– Room temperature
Molecular Formula
– C17H18O7
References
– [1]Ahmed M, et ,al. Analgesic sesquiterpene dilactone from Mikania cordata. Fitoterapia. 2001 Dec;72(8):919-21.|[2]Ysrael MC, et, al. Inhibition of leukotriene and platelet activating factor synthesis in leukocytes by the sesquiterpene lactone scandenolide. Planta Med. 1990 Jun;56(3):268-70.
CAS Number
– 23758-16-9
Molecular Weight
– 334.32
SMILES
– O=C1C2=C[C@@H](O1)C(C(C(O3)=O)=C)[C@@H]3C[C@@]4(C)[C@@H](O4)C[C@H]2OC(C)=O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Platelet-activating Factor Receptor (PAFR)
Pathway
– GPCR/G Protein
Product type
– Reference compound
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