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Products Details
Product Description
– Scaff10-8, bound to RhoA, inhibits the AKAP-Lbc-mediated RhoA activation[1].
Web ID
– HY-121667
Shipping
– Room temperature
Molecular Formula
– C22H18O6
References
– [1]Schrade K, et al. An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells. PLoS One. 2018;13(1):e0191423. Published 2018 Jan 26.
CAS Number
– 777857-56-4
Molecular Weight
– 378.37
SMILES
– O=C(CCC1=C(C2=CC3=C(C=C2OC1=O)OC=C3C4=CC=C(C=C4)OC)C)O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ROCK
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton;Stem Cell/Wnt;TGF-beta/Smad
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
