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Scaff10-8
SKU
HY-121667-Get quote
Category Reference compound
Tags Cancer, Cell Cycle/DNA Damage;Cytoskeleton;Stem Cell/Wnt;TGF-beta/Smad, ROCK
Products Details
Product Description
– Scaff10-8, bound to RhoA, inhibits the AKAP-Lbc-mediated RhoA activation[1].
Web ID
– HY-121667
Shipping
– Room temperature
Molecular Formula
– C22H18O6
References
– [1]Schrade K, et al. An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells. PLoS One. 2018;13(1):e0191423. Published 2018 Jan 26.
CAS Number
– 777857-56-4
Molecular Weight
– 378.37
SMILES
– O=C(CCC1=C(C2=CC3=C(C=C2OC1=O)OC=C3C4=CC=C(C=C4)OC)C)O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ROCK
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton;Stem Cell/Wnt;TGF-beta/Smad
Product type
– Reference compound
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