SC239

$810$3,250

Products Details

Product Description

– SC239 is a cleavable 2-aminophenyl hemiasterlin agent-linker. SC239 can be as the agent-linker for ADC[1]. SC239 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Web ID

– HY-148194

Storage Temperature

– 4°C (Powder, protect from light)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C65H84N10O11

References

– [1]Xiaofan Li, et al. Abstract 1782: Discovery and activity of STRO-002, a novel ADC targeting folate receptor alpha for ovarian and endometrial cancer. Cancer Res (2018) 78 (13_Supplement): 1782.

CAS Number

– 1977557-97-3

Molecular Weight

– 1181.42

Compound Purity

– 99.97

SMILES

– O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC(C=C4)=CC=C4COC(NC5=CC(C(C)(C)[C@H](NC)C(N[C@@H](C(C)(C)C)C(N(C)[C@@H](C(C)C)/C=C(C)/C(O)=O)=O)=O)=CC=C5)=O)=O)=O)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 75 mg/mL (ultrasonic)

Target

– Drug-Linker Conjugates for ADC

Pathway

– Antibody-drug Conjugate/ADC Related

Product type

– ADC Related

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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