Download Files:
Products Details
Product Description
– SC-19220 is a competitive prostaglandinn E2 receptor antagonist. SC-19220 increases the bladder capacity and reduced the voiding efficiency of micturition (elicited by slow transvesical filling) of urethane-anesthetized rats. SC-19220 can restores the balance in bone marrow granulocyte and monocyte production after burn sepsis[1][2].
Web ID
– HY-102065
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C16H14ClN3O3
References
– [1]Maggi CA, et al. The effect of SC-19220, a prostaglandin antagonist, on the micturition reflex in rats. Eur J Pharmacol. 1988 Aug 2;152(3):273-9.|[2]Santangelo S, Shoup M, Gamelli RL, Shankar R. Prostaglandin E2 receptor antagonist (SC-19220) treatment restores the balance to bone marrow myelopoiesis after burn sepsis. J Trauma. 2000 May;48(5):826-30; discussion 830-1.
CAS Number
– 19395-87-0
Molecular Weight
– 331.75
SMILES
– O=C(N1C2=CC(Cl)=CC=C2OC3=C(C1)C=CC=C3)NNC(C)=O
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Prostaglandin Receptor
Isoform
– EP
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
