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SBI-115
SKU
HY-111534-10 mg
Category Reference compound
Tags G protein-coupled Bile Acid Receptor 1, GPCR/G Protein, Others
$60 – $450
Products Details
Product Description
– SBI-115 is a TGR5 (GPCR19) antagonist. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5[1].
Web ID
– HY-111534
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C14H13ClN2O4S
References
– [1]Masyuk TV, et al. TGR5 contributes to hepatic cystogenesis in rodents with polycystic liver diseases through cyclic adenosine monophosphate/Gαs signaling. Hepatology. 2017 Oct; 66(4):1197-1218.
CAS Number
– 882366-16-7
Molecular Weight
– 340.78
Compound Purity
– 99.57
SMILES
– O=C(C1=NC(S(=O)(CC)=O)=NC=C1Cl)OC2=CC=CC(C)=C2
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : 150 mg/mL (ultrasonic)
Target
– G protein-coupled Bile Acid Receptor 1
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.