SBI-115

$60$450

Products Details

Product Description

– SBI-115 is a TGR5 (GPCR19) antagonist. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5[1].

Web ID

– HY-111534

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C14H13ClN2O4S

References

– [1]Masyuk TV, et al. TGR5 contributes to hepatic cystogenesis in rodents with polycystic liver diseases through cyclic adenosine monophosphate/Gαs signaling. Hepatology. 2017 Oct; 66(4):1197-1218.

CAS Number

– 882366-16-7

Molecular Weight

– 340.78

Compound Purity

– 99.57

SMILES

– O=C(C1=NC(S(=O)(CC)=O)=NC=C1Cl)OC2=CC=CC(C)=C2

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– DMSO : 150 mg/mL (ultrasonic)

Target

– G protein-coupled Bile Acid Receptor 1

Pathway

– GPCR/G Protein

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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