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SB1-G-187
$780 – $6,200
Products Details
Product Description
– SB1-G-187, a PROTAC, is a multi-kinase degrader[1]. SB1-G-187 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-137342
Storage Temperature
– -20°C (Powder, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Cancer-Kinase/protease
Molecular Formula
– C52H54F3N9O10
References
– [1]Katherine A Donovan, et al. Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development. Cell. 2020 Dec 10;183(6):1714-1731.e10.
CAS Number
– 2769753-18-4
Molecular Weight
– 1022.03
Compound Purity
– 98.01
SMILES
– O=C1N(C2CCC(NC2=O)=O)C(C3=C1C=CC=C3OCC(NCCOCCOCCOCCCN4CCN(CC5=C(C(F)(F)F)C=C(NC(C6=CC(C#CC7=CN=C8N7N=CC=C8)=C(C)C=C6)=O)C=C5)CC4)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– PROTACs
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
