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SB-328437
SKU
HY-103363-10 mg
Category Reference compound
Tags CCR, GPCR/G Protein;Immunology/Inflammation, Inflammation/Immunology
$120 – $980
Products Details
Product Description
– SB-328437 is a potent, selective non-peptide CCR3 antagonist with an IC50 of 4.5 nM[1].
Web ID
– HY-103363
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C21H18N2O5
References
– [1]White JR, et al. Identification of potent, selective non-peptide CC chemokine receptor-3 antagonist that inhibits eotaxin-, eotaxin-2-, and monocyte chemotactic protein-4-induced eosinophil migration. J Biol Chem. 2000 Nov 24;275(47):36626-31.Â
CAS Number
– 247580-43-4
Molecular Weight
– 378.38
Compound Purity
– 98.48
SMILES
– O=C(OC)[C@H](CC1=CC=C([N+]([O-])=O)C=C1)NC(C2=C3C=CC=CC3=CC=C2)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– CCR
Isoform
– CCR3
Pathway
– GPCR/G Protein;Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.