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Products Details
Product Description
– SARS-CoV-2 Mpro-IN-2 (compound GC-14) is a selective, low cytotoxic and non-covalent Mpro inhibitor (IC50=0.40 μM) with good anti-SARS-CoV-2 activity (EC50=1.1 μM). SARS-CoV-2 Mpro-IN-2 can be used in COVID-19 studies[1].
Web ID
– HY-151482
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C22H20Cl2N4O2S
References
– [1]Gao S, et al. Discovery and Crystallographic Studies of Trisubstituted Piperazine Derivatives as Non-Covalent SARS-CoV-2 Main Protease Inhibitors with High Target Specificity and Low Toxicity. J Med Chem. 2022 Sep 15:acs.jmedchem.2c01146.
CAS Number
– 2768834-39-3
Molecular Weight
– 475.39
SMILES
– O=C(C1=CN=CC=C1)N2C[C@@H](C(NCC3=CC=CS3)=O)N(C4=CC(Cl)=C(C=C4)Cl)CC2
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– SARS-CoV
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
