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Products Details
Product Description
– SARS-CoV-2 3CLpro-IN-19 (Compound C5a) is a non-covalent, non-peptide SARS-CoV-2 3CLpro inhibitor (IC50s: 0.7 μM). SARS-CoV-2 3CLpro-IN-19 has broad-spectrum activity against Omicron subvariants (BA.5, BQ.1.1, and XBB.1.5) infection in human cells, with EC50 values between 30-69 nM[1].
Web ID
– HY-155186
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C24H22ClN3O2S
References
– [1]Pérez-Vargas J, et al. A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerg Microbes Infect. 2023 Dec;12(2):2246594.
Molecular Weight
– 451.97
SMILES
– CN(C)C1=CC=C(N(C(CC2=C(C(O)=CC=C3)C3=CN=C2)=O)CC4=CC(Cl)=CS4)C=C1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– SARS-CoV
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
