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SARS-CoV-2 3CLpro-IN-18
Products Details
Product Description
– SARS-CoV-2 3CLpro-IN-18 (Compound 3C) is a covalent SARS-CoV-2 3CLpro inhibitor (IC50s: 0.478 μM). SARS-CoV-2 3CLpro-IN-18 inhibits SARS-CoV-2 in Vero E6 cells (EC50= 2.499 μM) with low cytotoxicity (CC50 > 200 μM)[1].
Web ID
– HY-155981
Shipping
– Room temperature
Molecular Formula
– C17H13ClN2OS
References
– [1]Ren P, et al. Discovery and Mechanism Study of SARS-CoV-2 3C-like Protease Inhibitors with a New Reactive Group. J Med Chem. 2023 Aug 18.
Molecular Weight
– 328.82
SMILES
– O=C(N1C2=CC(Cl)=CC=C2CCC3=CC=CC=C31)CSC#N
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– SARS-CoV
Pathway
– Anti-infection
Product type
– Reference compound
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