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Products Details
Product Description
– SARS-CoV-2 3CLpro-IN-14 (compound 11j) is an orally active SARS-CoV-2 3CLpro inhibitor. SARS-CoV-2 3CLpro-IN-14 shows significant anti-SARS-CoV-2 activity (EC50 = 0.18 μM) and low cytotoxicity (CC50 > 50 μM) in Vero E6 cells[1].
Web ID
– HY-155540
Shipping
– Room temperature
Molecular Formula
– C34H40F3N5O6S2
References
– [1]Yang H, et al. Design, synthesis and biological evaluation of peptidomimetic benzothiazolyl ketones as 3CLpro inhibitors against SARS-CoV-2. Eur J Med Chem. 2023 Sep 5;257:115512.
Molecular Weight
– 735.84
SMILES
– FC(F)(F)S(=O)(N[C@H](C(N1[C@@H](C2)CC[C@@H]2[C@H]1C(N[C@H](C(C3=NC4=CC=CC=C4S3)=O)C[C@@H]5CCNC5=O)=O)=O)C6(C7)C[C@@H](C8)C[C@H]7C[C@@H]8C6)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– SARS-CoV
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
