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Saroglitazar (magnesium)
$180 – $2,160
Products Details
Product Description
– Saroglitazar magnesium is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity with EC50 values of 0.65 pM and 3 nM in HepG2 cells, respectively.
Web ID
– HY-19937A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C50H56MgN2O8S2
Citations
– BMC Complement Med Ther. 2021 Apr 10;21(1):118.|Patent. US20210275504A1.|Cell Biol Toxicol. 2020 Jul 1. |Patent. US20190388398A1.
References
– [1]Jain MR, et al. Saroglitazar, a novel PPARα/γ agonist with predominant PPARα activity, shows lipid-lowering effects in preclinical models. Pharmacol Res Perspect. 2015 Jun;3(3):e00136.
CAS Number
– 1639792-20-3
Molecular Weight
– 901.42
Compound Purity
– 98.85
SMILES
– CCO([Mg+2]1(O(CC)[C@H](C([O-]1)=O)CC2=CC=C(OCCN3C(C)=CC=C3C4=CC=C(SC)C=C4)C=C2)[O-]C5=O)[C@H]5CC6=CC=C(OCCN7C(C)=CC=C7C8=CC=C(SC)C=C8)C=C6
Clinical Information
– Phase 4
Research Area
– Metabolic Disease
Solubility
– DMSO : 125 mg/mL (ultrasonic)
Target
– PPAR
Isoform
– PPARα;PPARγ
Pathway
– Cell Cycle/DNA Damage;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
