Sarcosine-d3

$60$90

Products Details

Product Description

– Sarcosine-d3 is the deuterium labeled Sarcosine. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia[1][2].

Web ID

– HY-101037S1

Storage Temperature

– -20°C, 3 years (Powder)

Shipping

– Blue Ice

Applications

– Cancer-programmed cell death

Molecular Formula

– C3H4D3NO2

References

– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Katarzyna SocaÅ‚a, et al. Effects of sarcosine, a glycine transporter type 1 inhibitor, in two mouse seizure models. Pharmacol Rep. Mar-Apr 2010;62(2):392-7.|[3]Mei-Yi Lee, et al. Effects of sarcosine and N, N-dimethylglycine on NMDA receptor-mediated excitatory field potentials. J Biomed Sci. 2017; 24: 18.

CAS Number

– 118685-91-9

Molecular Weight

– 92.11

Compound Purity

– 98.0

SMILES

– O=C(O)CNC([2H])([2H])[2H]

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– H2O : 125 mg/mL (ultrasonic)

Target

– Endogenous Metabolite;GlyT;Isotope-Labeled Compounds

Isoform

– GlyT1

Pathway

– Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling;Others

Product type

– Isotope-Labeled Compounds

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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