Download Files:
Products Details
Product Description
– Sanguinarine (Sanguinarin) gluconate, a benzophenanthridine alkaloid, can stimulate apoptosis via activating the production of reactive oxygen species (ROS). Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB[1].
Web ID
– HY-N0052C
Shipping
– Room temperature
Molecular Formula
– C26H25NO11
References
– [1]Wang Y, Noninvasive bioluminescence imaging of the dynamics of sanguinarine induced apoptosis via activation of reactive oxygen species. Oncotarget. 2016 Apr 19;7(16):22355-67.
CAS Number
– 132210-34-5
Molecular Weight
– 527.48
SMILES
– OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.C[N+]1=CC2=C3C(OCO3)=CC=C2C4=C1C5=CC6=C(OCO6)C=C5C=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Reactive Oxygen Species
Pathway
– Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
