Download Files:
SAG-d3
$220 – $800
Products Details
Product Description
– SAG-d3 is deuterium labeled SAG. SAG is a potent Smoothened (Smo) receptor agonist (EC50=3 nM; Kd=59 nM)[1].
Web ID
– HY-12848S
Storage Temperature
– -20°C (Powder, protect from light, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C28H25D3ClN3OS
References
– [1]Chen JK, et al. Small molecule modulation of Smoothened activity. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14071-6.
Molecular Weight
– 493.08
Compound Purity
– 99.85
SMILES
– ClC1=C(SC2=CC=CC=C21)C(N(CC3=CC=CC(C4=CC=NC=C4)=C3)[C@H]5CC[C@@H](CC5)NC([2H])([2H])[2H])=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Smo
Pathway
– Stem Cell/Wnt
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
