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Sabcomeline
SKU
HY-106432-Get quote
Category Reference compound
Tags GPCR/G Protein;Neuronal Signaling, mAChR, Neurological Disease
Products Details
Product Description
– Sabcomeline (SB-202026) is a potent and functionally selective muscarinic M1 receptor partial agonist that improve cognition. Sabcomeline can be used for Alzheimer’s disease research[1][2].
Web ID
– HY-106432
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C10H15N3O
References
– [1]Hosoi R, et al. Effect of sabcomeline on muscarinic and dopamine receptor binding in intact mouse brain. Ann Nucl Med. 2003;17(2):123-130. |[2]Hatcher JP, et al. Sabcomeline (SB-202026), a functionally selective M1 receptor partial agonist, reverses delay-induced deficits in the T-maze. Psychopharmacology (Berl). 1998;138(3-4):275-282.
CAS Number
– 159912-53-5
Molecular Weight
– 193.25
SMILES
– CO/N=C([C@@H]1C2CCN(CC2)C1)C#N
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– mAChR
Isoform
– mAChR1
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.