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S29434
$150 – $1,400
Products Details
Product Description
– S29434 (NMDPEF) is a potent, competitive, selective and cell-permeable inhibitor of quinone reductase 2 (QR2), with IC50s ranging from 5 to 16 nM for human QR2 at different organizational levels, and has good selectivity for QR2 over QR1. S29434 induces autophagy and inhibits QR2-mediated ROS production[1].
Web ID
– HY-122614
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C21H18N4O3
References
– [1]Boutin JA, et al. S29434, a Quinone Reductase 2 Inhibitor: Main Biochemical and Cellular Characterization. Mol Pharmacol. 2019 Mar;95(3):269-285.
CAS Number
– 874484-20-5
Molecular Weight
– 374.39
Compound Purity
– 99.25
SMILES
– O=C(C1=CC=CO1)NCCC2=C(C3=NC=CC=C3C4)N4C5=CC=C(OC)N=C52
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 19.29 mg/mL (ultrasonic)
Target
– Autophagy
Pathway
– Autophagy
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
