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Products Details
Product Description
– S217879 is a highly potent and selective NRF2 activator. S217879 disrupts the KEAP1-NRF2 interaction leading to robust NRF2 pathway activation. S217879 can be used for non-alcoholic steatohepatitis (NASH) research[1].
Web ID
– HY-156065
Shipping
– Room temperature
Molecular Formula
– C29H30N4O7S
References
– [1]Seedorf K, et al. Selective disruption of NRF2-KEAP1 interaction leads to NASH resolution and reduction of liver fibrosis in mice. JHEP Rep. 2022 Dec 16;5(4):100651.
Molecular Weight
– 578.64
SMILES
– O=S(OC1=C2C=C(OCCOCCN3C(C=C([C@H](C4=CC=CC([C@H]5C)=C4)CC(O)=O)C=C6C)=C6N=N3)C=C1)(N5C2)=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Keap1-Nrf2
Pathway
– NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
