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Products Details
Product Description
– S1PR1 modulator 1 is a selective S1PR1 inhibitor, with a pIC50 of 7.6, with >40- and >80-fold selectivity, over the other S1PR isoforms S1PR2/3/4[1].
Web ID
– HY-126145
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C23H24N2O3S
References
– [1]Bell M, et al. Discovery of Soft-Drug Topical Tool Modulators of Sphingosine-1-phosphate Receptor 1 (S1PR1). ACS Med Chem Lett. 2019 Feb 14;10(3):341-347.
CAS Number
– 2328109-05-1
Molecular Weight
– 408.51
SMILES
– CC1=CC=CC=C1N2C(/C(S/C2=NCCC)=C/C3=CC=C(OC(C)=O)C(C)=C3)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– LPL Receptor
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
