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Products Details
Product Description
– S1P1 agonist 4 has a better profile in both potency (EC50 < 0.05 mg/kg) and predicted human half-life (t1/2 ∼ 5 days).
Web ID
– HY-145362
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C24H31NO3
References
– [1]Xiao Z, et al. Aryl Ether-Derived Sphingosine-1-Phosphate Receptor (S1P1) Modulators: Optimization of the PK, PD, and Safety Profiles. ACS Med Chem Lett. 2020 Aug 11;11(9):1766-1772.
CAS Number
– 1883345-11-6
Molecular Weight
– 381.51
SMILES
– OC[C@@]1(C[C@@](CC1)([H])C2=CC=C(C[C@@H](CC3)COC4=CC(OC)=CC=C4)C3=C2)N
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– LPL Receptor
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
