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(S)-WAY 100135 (dihydrochloride)

Products Details

Product Description

– (S)-WAY 100135 dihydrochloride is a highly selective and potent antagonist of 5-HT 1A (IC50=33.9 nM). (S)-WAY 100135 dihydrochloride has anxiolytic activity in animal models[1].

Web ID

– HY-110001

Shipping

– Room temperature

Molecular Formula

– C24H35Cl2N3O2

References

– [1]Cliffe IA, et al. (S)-N-tert-butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide [(S)-WAY-100135]: a selective antagonist at presynaptic and postsynaptic 5-HT1A receptors. J Med Chem. 1993 May 14;36(10):1509-10.

CAS Number

– 149007-54-5

Molecular Weight

– 468.46

SMILES

– COC1=C(N2CCN(CC2)C[C@H](C3=CC=CC=C3)C(NC(C)(C)C)=O)C=CC=C1.Cl.Cl

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– 5-HT Receptor

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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