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(S)-WAY 100135 (dihydrochloride)
SKU
HY-110001-Get quote
Category Reference compound
Tags 5-HT Receptor, GPCR/G Protein;Neuronal Signaling, Neurological Disease
Products Details
Product Description
– (S)-WAY 100135 dihydrochloride is a highly selective and potent antagonist of 5-HT 1A (IC50=33.9 nM). (S)-WAY 100135 dihydrochloride has anxiolytic activity in animal models[1].
Web ID
– HY-110001
Shipping
– Room temperature
Molecular Formula
– C24H35Cl2N3O2
References
– [1]Cliffe IA, et al. (S)-N-tert-butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide [(S)-WAY-100135]: a selective antagonist at presynaptic and postsynaptic 5-HT1A receptors. J Med Chem. 1993 May 14;36(10):1509-10.
CAS Number
– 149007-54-5
Molecular Weight
– 468.46
SMILES
– COC1=C(N2CCN(CC2)C[C@H](C3=CC=CC=C3)C(NC(C)(C)C)=O)C=CC=C1.Cl.Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– 5-HT Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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