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Products Details
Product Description
– S-(+)-Mecamylamine (hydrochloride) is a neuronal nicotinic receptor modulator with antidepressant activity.
Web ID
– HY-13047
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C11H22ClN
References
– [1]Lippiello PM, Beaver JS, Gatto GJ, et al. TC-5214 (S-(+)-mecamylamine): a neuronal nicotinic receptor modulator with antidepressant activity. CNS Neurosci Ther. 2008;14(4):266-277. |[2]Vieta E, Thase ME, Naber D, et al. Efficacy and tolerability of flexibly-dosed adjunct TC-5214 (dexmecamylamine) in patients with major depressive disorder and inadequate response to prior antidepressant. Eur Neuropsychopharmacol. 2014;24(4):564-574.
CAS Number
– 107596-30-5
Molecular Weight
– 203.75
SMILES
– CN[C@]1([C@H]2C[C@H](CC2)C1(C)C)C.Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– nAChR
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
